Eforto® for Healthcare Professionals

Addressing Age-Related Frailty and Decline

The challenge of managing frailty and sarcopenia is central to geriatric medicine. Early identification and intervention are key to preserving independence and improving quality of life for older adults (Epidemiology – Frailty Science).

• Relevance: Grip strength is a core component of the frailty phenotype, and declining muscle function is a hallmark of sarcopenia. There is a significant need for practical tools to screen for these conditions before a crisis, like a fall, occurs.
• Application: Eforto offers a 5-minute, standardized test that can be easily integrated into annual wellness visits or geriatric assessments (Eforto Health). It quantifies maximal grip strength and, uniquely, muscle fatigability, providing a more sensitive indicator of declining physical reserves than strength alone.
• Clinical Impact: By flagging patients with low or declining muscle function, Eforto® enables timely interventions such as physical therapy, nutritional counseling, and falls prevention programs. Remote monitoring capabilities allow for tracking post-hospitalization recovery, helping to mitigate functional decline.

Strength and Fatigue Management in Cancer Care

Cancer and its treatments frequently lead to debilitating side effects, including cancer cachexia (muscle wasting) and severe cancer-related fatigue (CRF). Managing these conditions is critical for maintaining treatment tolerance and patient quality of life.

• Relevance: Muscle wasting affects up to 50–80% of patients with advanced cancer and is a direct cause of mortality. CRF is one of the most common and distressing symptoms reported by patients, affecting 70%–90% of those undergoing treatment.
• Application: Eforto provides an objective tool to monitor muscle function throughout the cancer journey. Regular assessments can detect the early onset of cachexia by tracking declines in strength and endurance, prompting earlier nutritional or rehabilitative support. For CRF, Eforto distinguishes physical fatigability from subjective tiredness, helping to tailor interventions and validate the patient's experience.
• Clinical Impact: Proactive monitoring with Eforto helps maintain a patient's strength, which can improve their ability to complete planned chemotherapy cycles and tolerate treatment. In survivorship, it serves as a motivational tool to track functional recovery and guide rehabilitation for the millions of cancer survivors worldwide.

Integrating Muscle Health into Routine Care

Primary care is the frontline of preventive medicine. Integrating a quick, objective measure of muscle health and frailty can shift the focus from reactive treatment to proactive health management for aging adults.

• Relevance: Grip strength is a powerful predictor of future morbidity, hospitalization, and all-cause mortality. It serves as a simple "vital sign" for overall physiological resilience.
• Application: The 5-minute Eforto® test can be seamlessly incorporated into physicals or wellness clinic’ visits. A low or declining score on grip strength or muscle endurance can trigger further investigation or referrals for preventive care, such as nutrition counseling or physical therapy.
• Clinical Impact: Eforto® empowers primary care providers to identify at-risk individuals early, long before functional decline becomes apparent. This creates opportunities for preventive interventions that can delay the onset of frailty, manage chronic conditions more effectively, and reduce downstream healthcare costs.

Enhancing Surgical Outcomes and Recovery

A patient's physical reserve is a critical determinant of their ability to withstand the stress of major surgery or critical illness. Assessing frailty pre-operatively and tracking recovery post-operatively are key to improving outcomes.

• Relevance: Frailty significantly increases the risk of postoperative complications, longer hospital stays, and mortality. Similarly, ICU-acquired weakness affects 25–50% of patients with prolonged ICU stays, leading to long-term disability.
• Application: Eforto® can be used in pre-surgical clinics as a rapid screening tool for frailty, identifying high-risk patients who would benefit from prehabilitation. Post-operatively or after an ICU stay, Eforto® enables remote monitoring of a patient's strength and endurance recovery, providing a quantitative trajectory that can alert clinicians to setbacks or suboptimal progress.
• Clinical Impact: Integrating Eforto® into the perioperative pathway facilitates data-driven decisions. It helps optimize patients for surgery through targeted prehab, supports safer discharge planning, and allows for timely intervention if post-discharge recovery falters, ultimately reducing complications and readmissions.

Managing Heart Failure and Cardiac Rehab

Heart failure is a systemic condition where muscle weakness and frailty are highly prevalent and are strong predictors of poor outcomes.

• Relevance: Approximately 50% of heart failure patients are frail, which significantly increases their risk of hospitalization and mortality.
• Application: In heart failure clinics, Eforto® provides a quick, objective measure of frailty status, helping to stratify risk and guide therapeutic decisions. As part of a remote patient monitoring (RPM) program, a decline in grip strength can act as an early warning sign of clinical decompensation. For cardiac rehabilitation, Eforto® tracks improvements in muscle endurance, providing objective feedback that can enhance patient motivation and adherence, addressing the challenge that only 20-30% of eligible patients enroll in these vital programs.
• Clinical Impact: By making frailty a measurable vital sign in cardiology, Eforto® helps personalize care for high-risk heart failure patients. It enhances the effectiveness of cardiac rehabilitation and provides a new data stream for remote monitoring programs, contributing to reduced hospitalizations and improved functional capacity.

Supporting Neurorehabilitation and Neuromuscular Monitoring

Neurological conditions are often characterized by progressive weakness and significant fatigue. Objective, frequent measurement is essential for tracking disease progression, titrating therapies, and guiding rehabilitation.

• Relevance: Conditions like Stroke, Multiple Sclerosis (MS), ALS, and Myasthenia Gravis (MG) all involve impaired neuromuscular function that fluctuates and requires careful monitoring.
• Application: Eforto® serves as a versatile tool across neurology. In stroke rehab, it quantifies motor recovery in the affected limb, providing motivating feedback for patients among the 93.8 million global survivors. For MS patients, it offers an objective measure of physical fatigability to complement subjective reports and guide energy management strategies. In progressive diseases like ALS, frequent home monitoring can track the rate of decline with higher resolution than clinic visits, providing valuable data for care planning and clinical trials.
• Clinical Impact: Eforto® makes neuromuscular assessment more data-driven. It provides objective endpoints for clinical trials, enhances the precision of rehabilitation programs, and empowers patients and clinicians with quantitative insights to better manage the functional impact of neurological disease.

Frailty in COPD, Kidney Disease, and Post-COVID

Systemic inflammation and catabolism in many chronic diseases accelerate muscle loss and frailty, worsening prognosis and quality of life.

• Relevance: Muscle weakness is a key comorbidity in COPD, chronic kidney disease (CKD), and is a persistent symptom for many with Post-COVID Syndrome. This weakness limits exercise capacity and increases mortality risk.
• Application: Eforto® offers a simple, non-exertional way to monitor systemic muscle health in patients who cannot perform traditional exercise tests. It can track the impact of pulmonary rehabilitation, monitor the effects of dialysis on muscle endurance in CKD, and quantify functional recovery in Post-COVID patients.
• Clinical Impact: By providing a reliable proxy for overall muscle health, Eforto® helps clinicians manage the systemic effects of chronic diseases, assess the efficacy of interventions, and objectively track a patient’s functional status over time.

Enhancing Workplace Safety and Recovery

In physically demanding industries, managing employee fatigue is crucial for preventing costly injuries and ensuring a safe work environment.

• Relevance: Grip strength and muscle endurance serve as objective indicators of an employee's physical readiness. A significant drop in performance can signal fatigue or burnout risk, which are leading contributors to workplace accidents.
• Application: Eforto® can be utilized for pre-employment baseline testing to ensure candidates meet the physical demands of a role. It also functions as a tool to monitor fatigue during shifts and to objectively track functional recovery after a workplace injury, supporting evidence-based return-to-work decisions.
• Operational Impact: Eforto® provides occupational health managers with a simple, quantitative tool to mitigate injury risk, manage employee fatigue proactively, and create safer work protocols.

Optimizing Performance and Recovery

For athletes and athletic programs, the margin between peak performance and overtraining is narrow. Managing training loads and recovery is essential for preventing injuries and achieving competitive goals.

• Relevance: Grip strength and muscle endurance are reliable indicators of neuromuscular readiness and central nervous system fatigue. A notable decline can signal overtraining risk before performance overtly suffers.
• Application: Eforto® can be used as a daily "readiness-to-perform" check for athletes. The objective data helps coaches and trainers make informed decisions to guide daily training loads, ensuring athletes are pushed optimally without being pushed into a state of overtraining.
• Performance Impact: Eforto® equips coaches, trainers, and sports medicine professionals with a simple, quantitative tool to personalize training, mitigate injury risk, and ensure athletes are physiologically ready for peak performance.

Quantifying Physical Resilience for Healthy Aging

• Relevance: Longevity clinics focus on optimizing biological age and functional capacity across the lifespan. Frailty and sarcopenia are major accelerators of biological aging and can undermine the benefits of precision medicine and anti-aging interventions.
• Application: Eforto® enables routine, longitudinal tracking of muscle strength and endurance—two hallmarks of physical vitality. By integrating Eforto® into biological age assessments, clinics can establish a personalized functional baseline and monitor the effects of interventions such as hormone therapy, exercise regimens, or nutraceuticals.
• Clinical Impact: Objective muscle performance data adds a new dimension to biological age scoring systems, providing actionable insight into physical reserve. Over time, Eforto® can demonstrate the effectiveness of interventions in reversing or slowing down functional decline, empowering patients with feedback and motivating adherence to healthy aging strategies.

Disentangling Physical from Perceived Fatigue

• Relevance: Chronic fatigue syndromes, including Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), long COVID, and fibromyalgia, are characterized by debilitating fatigue not always explained by conventional tests. Differentiating between physical fatigability and subjective tiredness is a major diagnostic and management challenge.
• Application: Eforto® provides a unique capability to measure muscle fatigability objectively, distinguishing it from self-reported symptoms. Clinicians can track changes over time and assess treatment responses—whether through graded activity, pacing, pharmacologic interventions, or lifestyle modifications—using standardized, reproducible metrics.
• Clinical Impact: By quantifying the physiological component of fatigue, Eforto® supports more precise diagnosis and targeted interventions. It also provides validation to patients whose symptoms are often misunderstood or minimized, enhancing therapeutic alliance and enabling personalized rehabilitation strategies.

Early Detection of (Sub)Clinical Frailty

• Relevance: Pharmacies are increasingly becoming community health hubs, well-positioned to detect early signs of health deterioration. Frailty often develops silently and is only recognized after adverse events like falls, hospitalizations, or rapid functional decline.
• Application: With its 5-minute protocol and portable device, Eforto® is ideal for pharmacy-based screening programs. Pharmacists can integrate muscle function assessments into medication reviews or wellness campaigns, identifying individuals with low strength or high fatigability who may benefit from early intervention or referral.
• Public Health Impact: By making frailty screening more accessible, Eforto® empowers pharmacies to play a key role in preventative care. Early detection of declining muscle health enables timely lifestyle or medical interventions, helping to reduce the burden of avoidable hospitalizations and preserve independence among aging adults.

Proper nutrition is essential for preserving muscle mass, physical strength, and overall health

• Relevence: Malnutrition, sarcopenia, and frailty are common but often unnoticed issues that can lead to serious health problems. Grip strength is a crucial indicator of nutritional status, treatment monitoring and a key measure of physical capacity in older adults, with its decline signaling frailty, cachexia, malnutrition risk, and reduced physical function.
• Application: Eforto® Eforto® empowers dietitians with objective, real-time data on muscle function, enabling tailored nutrition plans based on each patient’s physical reserves. Its mobile platform supports continuous monitoring of nutritional outcomes, ensuring early intervention, treatment tracking and personalized care in both remote and in-person settings.
• Public Health Impact: Eforto® enables widespread screening for malnutrition and muscle loss, allowing early dietary interventions. This helps reduce hospital stays, supports recovery, and promotes healthier aging across populations.

Broadening Reach

The future of healthcare is proactive and decentralized. Eforto® is designed to support scalable preventive health models and enhance telehealth services.

• Relevance: Effective telemedicine and remote patient monitoring (RPM) require objective, reliable data that can be collected by patients at home.
• Application: Eforto®’s self-guided mobile app and validated vigorimeter are ideal for telehealth and RPM programs focused on healthy aging, chronic disease management, or post-discharge care. Health coaches and care managers can remotely track their clients' physical reserves and intervene when they see a negative trend.
• Clinical Impact: Eforto® extends the reach of clinicians beyond the hospital walls. It enables scalable, cost-effective monitoring of at-risk populations, facilitating preventive care that keeps people healthier and more independent at home.