Eforto® for Clinical Research: Capture High-Quality Functional Endpoints

Advance your research with a validated, patient-centric system for monitoring muscle health and vitality. Eforto® provides objective, high-frequency data to enhance trial efficiency, sensitivity, and the quality of your outcomes.

A Growing Need for Smarter Functional Biomarkers:

Clinical trials in geriatrics, neurology, and chronic disease management face a significant challenge: the lack of sensitive, objective, and reliable outcome measures to track disease progression and therapeutic response.

Traditional assessments are often infrequent and burdensome for participants and may miss subtle but clinically meaningful changes.

There is a clear need for validated digital health technologies that allow for objective, remote monitoring of function, providing richer data between clinic visits and capturing real-world patient status

Better Functional Biomarkers

Bridging The Gap: Eforto®'s Validated, Remote Monitoring System

Eforto® is a complete system designed for the rigorous demands of clinical research. Our patented pneumatic vigorimeter, guided mobile app, and secure data platform empower you to capture validated biomarkers of neuromuscular function and vitality capacity with exceptional ease and precision.

Key Benefits for Researchers

Validated and Emerging Biomarkers of Muscle Function with Eforto®

Capture Core Validated Biomarkers

Move beyond subjective scales. Eforto® measures objective, WHO-aligned biomarkers for vitality capacity, including:

Maximal Grip Strength
Maximal Grip Strength

A proven, trusted indicator of overall muscle strength and a key criterion for sarcopenia and frailty.

Muscle Fatigability
Muscle Fatigability (Grip Work)

A more sensitive biomarker than grip strength alone, shown to be more responsive to interventions and strongly correlates with inflammation and functional decline.

Capacity-to-Perceived Vitality
Capacity-to-Perceived Vitality (CPV) Ratio

A novel, clinically validated measure that combines objective endurance with subjective fatigue to detect pre-frailty with high accuracy.

Eforto®’s Advanced Expanding Library of Biomarkers

Our team is continuously working with research partners to validate and add new, nuanced biomarkers of muscle function. We can work with you to incorporate experimental and advanced metrics into your protocol, including:

Rate of Voluntary - icon
Rate of Voluntary Force Development

To assess muscle power and explosive strength.

Maximal Grip Strength
Grip Release / Rate of Voluntary Force Relaxation

To analyze muscle control and relaxation properties.

Bilateral Strength
Bilateral Strength & Strength Asymmetry

To compare strength between limbs, critical for neurological and orthopedic studies.

Bimanual Coordination
Bimanual Coordination

To evaluate the coordination of both hands.

Force Steadiness
Force Steadiness

To measure submaximal control and motor stability.

Task-Specific Tremor
Task-Specific Tremor

To quantify tremors during exertion using integrated sensors.

High-Frequency
Enable High-Frequency, Remote Data Collection

Reduce participant burden and increase data density. Eforto® is 5-minute, self-guided test can be performed by participants at home, allowing for daily or weekly data collection that is impossible with traditional clinic-based tests. This provides a more granular view of disease progression or treatment effects.

Improve Trial Efficiency and Sensitivity
Improve Trial Efficiency and Sensitivity

High-frequency, objective data can increase the statistical power of your studies, potentially allowing for smaller sample sizes or shorter trial durations. By capturing sensitive changes in muscle fatigability, you may detect a therapeutic signal earlier than with traditional endpoints.

Enhance Patient Adherence and Engagement
Enhance Patient Adherence and Engagement

The Eforto® system is designed for ease of use, even for frail individuals. The interactive app guides participants through the validated protocol, and the ability to see their progress can enhance motivation and long-term adherence to the study protocol.

Eforto® Offers Tailored Protocols to Fit Your Research Needs

We understand that every study is unique. The Eforto® platform is a configurable solution designed for flexibility, allowing you to build custom protocols that precisely match your research objectives. Go beyond standard metrics and integrate bespoke electronic Patient-Reported Outcomes (ePROs) and an expanding list of advanced biomarkers.

Incorporate Customized ePROs:

  • Seamlessly integrate study-specific questionnaires.
  • Administer validated scales for disease activity, quality of life, or other subjective endpoints.
  • Capture patient-reported data directly within the Eforto® Connect app workflow.

Eforto®: A System Built for Research Integrity and Scalability

Eforto® was developed in collaboration with leading academic partners and validated in multicenter clinical trials. Our platform is built to meet the needs of modern research.

  • Secure & Interoperable Platform: The Eforto® Metrics platform provides robust tools for subject management, data visualization, and customizable alerts. Our system is designed with security and privacy at its core and offers API integration capabilities for seamless data flow into your existing Electronic Data Capture (EDC) or analysis systems.
  • Superior Measurement Technology: The Eforto® vigorimeter's ergonomic, pneumatic design has been shown to be superior to traditional hydraulic dynamometers for measuring muscle fatigability in older and frail populations. It provides more comfortable, reliable, and sensitive measurements, ensuring the quality of your endpoint data.

Precision Redefined: Eforto® vs Traditional Dynamometers

Traditional Dynamometers

Interested in using Eforto® in your study? Partner with Us on Your Next Study

Eforto® is already being used by leading research institutions and is a key component of international studies, including collaborations with the World Health Organization (WHO).

Whether your focus is on frailty, sarcopenia, neuromuscular disease, post-surgical recovery, or the impact of nutritional and pharmacological interventions, Eforto® provides the validated, patient-centric endpoints you need.